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How tobacco smoke causes disease : the biology and behavioral basis for smoking-attributable disease : a report of the Surgeon General.

United States. Public Health Service. Office of the Surgeon General.

Rockville, MD : U.S. Dept. of Health and Human Services, Public Health Service, Office of the Surgeon General ; Washington, DC : For sale by the Supt. of Docs., U.S. G.P.O. 2010

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  • Title:
    How tobacco smoke causes disease : the biology and behavioral basis for smoking-attributable disease : a report of the Surgeon General.
  • Author: United States. Public Health Service. Office of the Surgeon General.
  • Subjects: Tobacco use -- Health aspects; Smoking -- Health aspects; Tobacco smoke pollution -- Health aspects; Tobacco -- adverse effects; Smoking -- adverse effects; Disease -- etiology; Tobacco Use Disorder -- complications; Tobacco Smoke Pollution -- adverse effects; Smoking -- Health aspects; Tobacco smoke pollution -- Health aspects; Tobacco use -- Health aspects; Government publications -- United States
  • Contents: 1: Introduction, evaluation of evidence on mechanisms of disease production, and summary. Introduction ; Evaluation of evidence on mechanisms of disease production ; Mechanisms of action: necessary, sufficient, or neither ; Description of evidence on mechanisms of disease production ; Scientific basis of the report ; Development of the report ; Major conclusions ; Chapter conclusions ; References -- 2: The changing cigarette. Introduction ; Cigarette design changes over the years ; New cigarette products ; Low-nicotine cigarettes ; Cigarette-like products ; Evaluation of new cigarette products ; New oversight of tobacco products ; Summary ; Conclusions ; References -- 3: Chemistry and toxicology of cigarette smoke and biomarkers of exposure and harm. Introduction ; Chemistry ; Biomarkers ; Summary ; Conclusions ; References -- 4: Nicotine addiction : past and present. Introduction ; Definition of nicotine addiction ; Tobacco constituents and pharmacokinetics ; Components of nicotine addiction ; Pathophysiology of nicotine addiction ; Genetics ; Prevalence and trajectory toward nicotine dependence ; Epidemiology of tobacco use and nicotine dependence in adults ; Trajectory of recovery or relapse ; Evidence summary ; Conclusion ; References -- 5: Cancer. Introduction ; Carcinogen exposure, metabolism, and DNA adducts ; DNA repair and conversion of adducts to mutations ; Gene mutations in tobacco-induced cancer ; Loss of mechanisms for growth control ; Other aspects ; Evidence summary ; Conclusions ; References -- 6: Cardiovascular diseases. Introduction ; Tobacco use and cardiovascular disease ; Secondhand tobacco smoke and cardiovascular disease ; Pathophysiology ; Hemodynamic effects ; Smoking and the endothelium ; Thrombogenic effects ; Inflammation ; Smoking and diabetes ; Lipid abnormalities ; Cardiovascular biomarkers ; Smoking cessation and cardiovascular disease ; Methods to reduce exposure ; Evidence summary ; Conclusions ; References.
    7: Pulmonary diseases. Introduction ; Smoking and respiratory defense mechanisms ; Oxidative stress ; Oxidative stress in chronic obstructive pulmonary disease ; Genetics of pulmonary disease and susceptibility to tobacco smoke ; Pathogenesis of emphysema ; Summary ; Evidence summary ; Conclusions ; Implications ; References -- 8: Reproductive and developmental effects. Introduction ; Review of epidemiologic literature on smoking ; Pathophysiological and cellular and molecular mechanisms of smoking ; Implications ; Evidence summary ; Conclusions ; References -- 9: A vision for the future. The global tobacco epidemic ; Reducing the risks from smoking ; Ending the tobacco epidemic ; Concluding remarks ; Appendix 9-1. Recommendations for future research ; Appendix 9-2. Ending the tobacco problem : a blueprint for the nation ; Appendix 9-3. Promoting healthy lifestyles : policy, program, and personal recommendations for reducing cancer risk ; References -- List of abbreviations -- List of tables and figures -- Definitions and alternative nomenclature of genetic symbols used in this report -- Index.
  • Publisher: Rockville, MD : U.S. Dept. of Health and Human Services, Public Health Service, Office of the Surgeon General ; Washington, DC : For sale by the Supt. of Docs., U.S. G.P.O.
  • Creation Date: 2010
  • Physical Description: xv, 704 pages : illustrations (some color) ; 28 cm.
  • Language: English
  • Identifier: ISBN9780160840784;ISBN0160840783
  • Source: 01GALI USG ALMA
  • OCLC Number: 699006773
  • NZ MMS ID: 9910081732402931
  • IZ MMS ID: 996665844102948$$IAUGUSTA
    994949733602939$$ICSU
    992053513602940$$IDALTON
    999416533802950$$IGASOU
    993179214302951$$IGSWU
    995294783902954$$IKSU
    9938632133902959$$IUGA
    992918123702960$$IUNG
    996811004602961$$IUWG
    996932134802962$$IVSU

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